Annegret Falkner, Princeton Neuroscience Institute, USA: Mapping the neural dynamics of dominance and defeat

Abstract:

Social experiences can have lasting changes on behavior and affective state.  In particular, repeated wins and losses during fighting can facilitate and suppress future aggressive behavior, leading to persistent high aggression or low aggression states.  We use a combination of techniques for multi-region neural recording, perturbation, behavioral analysis, and modeling to understand how nodes in the brain’s subcortical “social decision-making network” encode and transform aggressive motivation into action, and how these circuits change following social experience.