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Published on 05.07.24
Identification of the modulatory Ca2+-binding sites of acid-sensing ion channel 1a
Extracellular acidification occurs during neuronal activity, activating acid-sensing ion channels (ASICs). The calcium concentration is one of many factors that modulate ASIC activity. Here, we investigated how calcium affects ASIC1a gating, identifying binding sites in two extracellular cavities and in the pore entry.
Extracellular acidification occurs during neuronal activity, activating acid-sensing ion channels (ASICs). The calcium concentration is one of many factors that modulate ASIC activity. Here, we investigated how calcium affects ASIC1a gating, identifying binding sites in two extracellular cavities and in the pore entry.
Published on 02.07.24
A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid...
A team of biologists led by UNIL has developed a fluorescent lipid droplet reporter mouse, which allows the staining-free detection of these important lipid-storing organelles. Using this model, they show that LDs are highly abundant in the developing and adult brain.
A team of biologists led by UNIL has developed a fluorescent lipid droplet reporter mouse, which allows the staining-free detection of these important lipid-storing organelles. Using this model, they show that LDs are highly abundant in the developing and adult brain.
Published on 03.06.24
The Stem Cell Podcast: Prof. Shukry J Habib on Cutting-Edge Stem Cell Research and...
Listen to the interview of Prof. Shukry J Habib from the Department of Biomedical Science on the Stem Cell Podcast, starting at the 43-minute mark.
Listen to the interview of Prof. Shukry J Habib from the Department of Biomedical Science on the Stem Cell Podcast, starting at the 43-minute mark.
Published on 23.05.24
Inducible CXCL12/CXCR4-dependent extramedullary hematopoietic niches in the adrenal...
Frederica Schyrr, Alejandro Alonso Calleja, Anjali Vijaykumar, Jessica Sordet-Dessimoz, Sandra Gebhard, Rita Sarkis, Charles Bataclan, Silvia Ferreira Lopes, Aurélien Laurent Jean-Charles Oggier, Laurence L de Leval, Cesar Nombela-Arrieta, Olaia M. Naveiras
Frederica Schyrr, Alejandro Alonso Calleja, Anjali Vijaykumar, Jessica Sordet-Dessimoz, Sandra Gebhard, Rita Sarkis, Charles Bataclan, Silvia Ferreira Lopes, Aurélien Laurent Jean-Charles Oggier, Laurence L de Leval, Cesar Nombela-Arrieta, Olaia M. Naveiras
