Publications - Neuroinflammation UNIL-CHUV

Clottu A, Mathias A, Sailer AW, Schluep M, Seebach JD, Du Pasquier R, Pot C. EBI2 expression and function: robust in memory lymphocytes and increased by natalizumab in multiple sclerosis. Cell Rep. 2017 Jan 3;18(1):213-224.
Disanto G, Benkert P, Lorscheider J, Muller, S; Vehoff, J, Zecca C, Ramseier, S Achtnichts, L, Findling O, Nedeltchev K, Radue EW, Sprenger T, Stippich, C, Derfuss T, Louvion JF, Kamm, C, Mattle, HP, Lotter, C, Du Pasquier, R, Schluep M, Pot C, Lalive PH; Yaldizli O, Gobbi C, Kappos L, Kuhle J. The Swiss Multiple Sclerosis Cohort-Study (SMSC): a prospective Swiss wide investigation of key phases in disease evolution and new treatment options. PLoS One. 2016 Mar 31;11(3).
Peters A*, Fowler K*, Chalmin F, Merkler D, Kuchroo VK, Pot C. IL-27 Induces Th17 Differentiation in the Absence of STAT1 Signaling. J Immunol. 2015 Nov 1;195(9):4144-53.* These authors equally contributed to the work
Chalmin F, Rochemont V, Lippens C, Clottu A, Sailer AW, Merkler D, Hugues S, Pot C. Oxysterols regulate encephalitogenic CD4+ T cell trafficking during central nervous system autoimmunity. Journal of Autoimmunity, 2015 Jan; 56: 45-55.
Guéry L, Dubrot J, Lippens C, Brighouse D, Irla M, Pot C, Reith W, Waldburger JM, Hugues S. CpG-activated pDCs contributes as APCs in the generation of Th17 cells that promote tumor regression. Cancer Research, 2014 Nov 15;74(22):6430-40.
Wu C *, Pot C *, Apetoh L *, Thalhamer T, Zhu B, Lee Y, Rangachari M, Yosef N, Kuchroo VK. Metallothioneins negatively regulate IL-27-induced type 1 regulatory T-cell differentiation. PNAS, 2013 May 7;110(19):7802-7. *These authors equally contributed to the work
Berger H, Végran F, Chikh M, Gilardi F, Ladoire S, Bugaut H, Mignot G, Chalmin F, Bruchard M, Derangère V, Rébé C, Ryffel B, Pot C, Hichami A, Desvergne B, Ghiringhelli F and Apetoh L. Transactivation of SOCS3 by PPARy prevents IL-17-related cancer growth. Cancer Research, 2013 Jun 15; 73(12):3578-3590.
Bonal C, Baronnier D, Pot C, Benkhoucha M, Schwab ME, Lalive PH; Herrera P. Nogo-A downregulation improves insulin secretion in mice. Diabetes 2013 May; 62(5):1443-52.
Apetoh L *, Quintana F *, Pot C *, Joller N, Xiao S, Kumar D, Burns EJ, Sheer D, Weiner HL, Kuchroo VK. The Aryl hydrocarbon Receptor (AhR) interacts with c-Maf to promote the differentiation of IL-27-induced regulatory type 1 (Tr1) cell. Nat. Immunol. 2010 Sep ;11(9):854-61. *These authors equally contributed to the work
Pot C, Jin H, Awasthi A, Liu S, Lai C, Madan R, Sharpe A.H, Karp C.L, Miaw S, Ho I.C, and Kuchroo V.K. Cutting edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS That Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells. J Immunol. 2009 July 15; 183(2): 797-801.
Awasthi A, Riol-Blanco L, Jäger A, Korn T, Pot C, Galileos G, Bettelli E, Kuchroo V.K, Oukka M. Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells. J Immunol. 2009 May 15; 182(10):5904-8.
Pot C, Burkhard PR, Villard J, Landis T, Perrin L, Kaiser L, Lalive P.H. Human Herpesvirus-6 variant A encephalomyelitis. Neurology. 2008 Mar 18; 70(12): 974-6.
Pot C, Chizzolini C, Vokatch N, Tiercy J.M, Ribi C, Landis T, Perren F. Combined Antiviral-Immunosuppressive Treatment in HTLV1-Sjögren associated Myelopathy. Arch Neurol. 2006 Sep; 63 (9):1318-20.
Aloy M.A, Weinmann O, Pot C, Dodd D.A, Kasper H, Rülicke T, Rossi F, Schwab M.E. Synaptic destabilization by neuronal Nogo-A. Brain Cell Biol. 2006 Jun; 35(2-3):137-56.
Pot C, Oppliger R, Castillo V, Coeytaux A, Hauser C, Burkhard P.R. Apomorphine-induced eosinophilic panniculitis and hypereosinophilia in Parkinson disease. Neurology. 2005 Jan 25; 64 (2):392-3.
Pot C, Simonen M, Weinmann O, Schnell L, Christ F, Stoeckle S, Berger P, Rülicke T, Suter U, Schwab M.E. Nogo-A expressed in Schwann cells impairs axonal regeneration after peripheral nerve injury. J Cell Biol 2002.159 (1): 29-35.

REVIEW ARTICLES (PEER-REVIEWED JOURNALS)

Pot C, Quintana F, Kuchroo VK. Fine tuning of the immune response by the Aryl Hydrocarbon Receptor. Semin. Immunopathol. 2013 Nov; 35 (6); 613-613
Pot C. Aryl hydrocarbon receptor controls regulatory CD4+T cell function. Swiss Med Wkly. 2012 May 31;142:0.
Pot C, Apetoh L, Awasthi A, Kuchroo VK. Induction of regulatory Tr1 cells and inhibition of TH17 cells by IL-27. Semin Immunol. 2011 Dec; 23(6):438-45.
Pot C, Apetoh L, Kuchroo VK. Type 1 Regulatory T cells (Tr1) in autoimmunity. Semin Immunol. 2011 Jun;23(3):202-8.
Pot C *, Apetoh L *, Awasthi A, Kuchroo VK. Molecular Pathways in the Induction of Interleukin-27-Driven Regulatory Type 1 Cells. J Interferon Cytokine Res. 2010 June; 30 (6): 381-387.