Find a host lab

STEP 1

You have first to choose one laboratory, see below.
Contact thesis directors of interest and if they appreciate your CV, ask them to send you a confirmation by email that she/he agrees to act as your potential thesis director and confirms that you were in contact with her/him before applying.
You should mention her/his name in your application form (see STEP 2) to continue your application.

Host Labs

A-C

Laboratories	Thesis Directors	Subject proposed
Anesthesiology	Suter Marc	Understanding the neuro-immune mechanisms of chronic pain. Exploring the pathophysiology of spinal microglia in chronic pain condition.
Angiology	Rosenblatt-Velin Nathalie	lnvolvement of the natriuretic peptides in the development of genetically triggered thoracic aortic aneurysm.
Biomedical Data Science Center	Gottardo Raphael	Multiscale spatial data analysis to decipher responses to cancer treatment. Development of computational tools and methods for the analysis of high-dimensional spatial and single-cell data.
Biomedical sciences	Amati Francesca	Aging and muscle metabolism
Biomedical sciences	Habib Shukry James	Rejuvenating and Repairing Aged Bones. PhD in Regenerative Medicine and Nutrition
Biomedical sciences	Langlet Fanny	Plasticity of blood/hypothalamus interface for the regulation of energy balance. Investigating the impact of microbiota on tanycyte barrier controlling food intake
Biomedical sciences	Mansuy-Aubert Virginie	Nutrition and Gut Brain communication. Maternal Gut Microbiota-Embryo Interplay during Pregnancy: Unraveling the Link to Obesity and Type 2 Diabetes Risk.
Biomedical sciences	Tzanoulinou Stamatina	Brain circuitry and long-term effects of social trauma.
Center for Integrative Genomics	Benton Richard	Evolution of neural circuit structure and function
Center for Integrative Genomics	Croizier Sophie	Deciphering the genetic and anatomic complexity of hypothalamic circuits: Sexually dimorphic development of hypothalamic feeding-circuits
Center for Integrative Genomics	Fankhauser Christian	Plant responses to their light environment: from transcriptional reprogramming to developmental adaptations
Center for Integrative Genomics	Gambetta Maria Cristina	Wiring of regulatory elements to target genes in three dimensions. This project will investigate how 3D genome folding matures during cell differentiation and enables cell type specific gene expression programs.
Center for Integrative Genomics	Van Leeuwen Jolanda	Systematic analysis of genetic interactions : The deleteriousness of a mutation can depend upon the genetic background. For example, two patients carrying the same disease causal mutation may experience differences in disease severity. By mapping the effects of single and double mutants on a large scale, the student will try to understand when and how such genetic interactions occur
Clinical Neurosciences	Serino Andrea	Assessment and neurorehabilitation of cognitive functions using gamified activities in immersive virtual reality for patients with acquired brain injury. Conceptual development and scientific validation of therapeutic activities in immersive virtual reality.
Clinical Neurosciences	Sokolov Arseny	Neurotechnology for cognitive neurorehabilitation. Technology-assisted personalized cognitive assessment and neurorehabilitation.
Computational Biology	Ciriello Giovanni	Genetic and non-genetic mechanisms of cancer evolution

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G-O

Laboratories	Thesis Directors	Subject proposed
Gastroenterology and Hepatology	Gouttenoire Jérôme	Molecular virology and pathogenesis of hepatitis C and E. Investigating the host factors required for hepatitis E virus (HEV) life cycle
Geriatrics	D'Amelio Patrizia	The main topics of interest are inflammaging and the role of mitochondria and oxidative stress in aging related diseases as bone metabolic disorders, cognitive impairment and sarcopenia. Maintaining Immune and Mitochondrial functions in Old adults with SAfe nutrition: the MIMOSA study.
Immunobiology	Broz Petr	The Broz lab investigates the innate immune signaling pathways that allows cells to detect and respond to the infection with pathogenic microorganisms. A particular focus of the lab is the inflammasome, a multi protein signaling platform that is assembled by pattern recognition receptors upon detection of pathogen- or host-derived danger signals, and which controls the release of cytokines and the induction of pyroptosis, a lytic for of cell death.
Immunobiology	Esser-von Bieren Julia	Regulation of type 2 immune responses. Cyclooxygenase metabolites as regulators of macrophage reprogramming in severe type-2 inflammation
Immunobiology	Martinon Fabio	Physiological mechanisms of autoinflammation in health and diseases
Infectious Diseases	Roger Thierry	Harnessing innate immune training to improve sepsis management
Information Systems	Villa Alessandro	Mindscope: Bridging the gap between fNIRS and neuronal dynamics during decision making
Institute of Sport Sciences of the University of Lausanne (ISSUL)	Place Nicolas	Neuromuscular plasticity to exercise / disease: : (i) skeletal muscle plasticity with a translational approach (from cell to human) or (ii) neuromuscular adaptations to exercise
Metabolomics Unit	Ivanisevic Julijana	Deep annotation of model organism metabolome along with lipidome
Microbiology	Ciuffi Angela	Impact of epitranscriptomic modifications on HIV life cycle. Investigation of the role of m5C on HIV translation and investigation of the role of candidate factors, identified in an epitranscriptomic analysis, on HIV replication.
Microbiology	Opota Onya	Mycobacterium tuberculosis Drug Resistance and Antibiotic Susceptibility Testing
Obstetrics, Gestational diabetes	Puder Jardena	Gestational diabetes, food viewing and metabolic health outcomes. Relationships between eating behavior, brain responses to food viewing, and metabolic health outcomes
Ophtalmology	Ansar Muhammad	The discovery of new inherited retinal dystrophy genes and therapeutic interventions. Human genetics.

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D-F

Laboratories	Thesis Directors	Subject proposed
Dermatology	Kuonen François	Characterization and targeting of skin cancer plasticity to prevent progression and resistance to therapy
Ecology and Evolution	Chapuisat Michel	Social evolution in ants. Potential subjects: Variation in social organization, social supergene evolution, population genomics
Ecology and Evolution	Kawecki Tadeusz	Using experimental evolution with Drosophila to understand adaptation and sexual selection. Various experimental projects using Drosophila as the study system to address evolutionary questions are possible. In particular, we study (1) adaptation to chronic juvenile undernutrition and (2) sexual selection and conflict.
Ecology and Evolution	Pannell John	Evolution and ecology of plant range margins and sexual systems
Ecology and Evolution	Robinson-Rechavi Marc	Evolutionary bioinformatics: Bioinformatics of animal evo-devo, specific subject to determine with the candidate
Ecology and Evolution	Schwander Tanja	Evolution of reproductive and genetic systems
Ecology and Evolution	Wedekind Claus	Evolutionary Conservation Biology
Endocrinology, Diabetology and Metabolism	Sykiotis Gerasimos	Roles of the antioxidant response system in the thyroid gland.
Forensic Genetics Units	Hall Diana	Development of novel genetic markers and data analysis for inferring biogeographic ancestry in humans. Follow-up to this study: "Inferring biogeographic ancestry with compound markers of slow and fast evolving polymorphisms." Moriot A, Santos C, Freire-Aradas A, Phillips C, Hall D. Eur J Hum Genet. 2018.
Fundamental Microbiology	Collier Justine	Regulation of the bacterial cell cycle. 2 potential topics: - Charaterization of restriction-modification systems in Caulobacter crescentus (DNA methylation/cleavage, phage defense systems, impact on horizontal gene transfers). - Epigenetic regulation in the Agrobacterium tumefaciens plant pathogen (DNA methylation, transcriptional regulation, genome replication).
Fundamental Microbiology	Mitri Sara	Artificial selection of small bacterial communities
Fundamental Microbiology	Schaerli Yolanda	Bacterial Synthetic Biology.Diverse projects in bacterial synthetic biology, including: - CRISPR-based circuits - Engineered living materials - Engineering the honey bee gut microbiome - Circuits for spatiotemporal pattern formation
Fundamental Microbiology	Veening Jan-Willem	Pneumococcal cell biology
Fundamental Microbiology	Vonaesch Pascale	Phage therapy to control human Streptococcus salivarius associated with inflammation in the intestinal tract of stunted children.
Fundamental Neurosciences	Bezzi Paola	Investigating the role of astrocytes in behavioural impairments associated with Phelan McDermid syndrome
Fundamental Neurosciences	Bagni Claudia	Mechanisms and Therapies for Autism and Fragile X Syndrome. Unlocking the Secrets of the Mind: Unraveling the Mysteries of Human Brain Organoids
Fundamental Neurosciences	Nikoletopoulou Vassiliki	Autophagic pathways of brain homeostasis
Fundamental Neurosciences	Puyal Julien	Autophagy, cell death and neuroprotection in perinatal brain injuries. Investigating the role of autophagy in oligodendrocytes in perinatal cerebral hypoxia-ischemia.
Fundamental Oncology	Ho Ping-Chih	Immunometabolic modulation controlling gender-biased immunity against infection and tumor
Fundamental Oncology	Petrova Tatiana	PhD in cancer and vascular biology. Immune-vascular communications in development and cancer
Fundamental Oncology	Verdeil Gregory	Regulation of immune dysfunction in cancer. Decipher the resistance to immune checkpoint inhibitors in advanced bladder cancer to develop new immunotherapeutic strategies.

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P-Z

Laboratories	Thesis Directors	Subject proposed
Plant Molecular Biology	Soyk Sebastian	Dissecting the genetic and molecular mechanisms of stem cell control. The aim of this PhD project will be to investigate genetic networks that control the activity of stem cell and were selected during domestication.
Psychiatric Neurosciences	Toni Nicolas	Adult hippocampal neurogenesis and its implication in psychiatric diseases. Study the role of the mechanisms of regulation of adult neurogenesis by the neurogenic niche in the context of anxiety disorders or cognitive impairment.
Psychiatry	Chabane Nadia	Sensorimotor development in Autism. A longitudinal assessment of first signs, the emergence of core symptoms and the role of early intervention.
Radiology	Murray Micah	Multisensory processes across the lifespan and development of human brain imaging and brain mapping methods
Radiology	Richiardi Jonas	Machine learning on medical images and -omics data for diagnosis, prognosis, and treatment planning. Deep learning for imaging genetics
Transplantation Centre & Service of Immunology	Golshayan Déla	Innate and adaptative immune determinants of graft outcome after solid organ transplantation. Immune profiling of rejection episodes and outcome after kidney transplantation
Unisanté - Epidemiology and health systems	Avendano Mauricio	The impact of public policies and health systems on population health, both in Swtizerland and globally, particularly on mental health and cognition. The impact of mental health policies
Unisanté - Epidemiology and health systems	Kutalik Zoltan	Statistical human genetics. Multi-layered evidence for gene expression optimality
Unisanté - Occupational and environmental epidemiology	Guseva Canu Irina	Ethiology of breast cancer: - Cancer du Sein et Travail de Nuit (CaSeTraN) - Burden of occupational cancers in Switzerland: Burden of asbestos-related cancers in Switzerland (BARCS)
Unisanté - Vulnerabilities and social medicine	Bodenmann Patrick	Improving health equity among populations in vulnerable situations
Urology	Derré Laurent	Immune regulation in urological malignancies.
Vascular surgery	Allagnat Florent	Dietary intervention and hydrogen sulfide to protect against vascular diseases
Women - Mother - Child	Stojanov Milos	Characterisation of seminal microbiota and its impact on human sperm. This ambitious PhD project has three main goals: - Characterise human seminal microbiota using next generation sequencing. - Isolate and identify bacteria from human semen to establish a collection of seminal bacteria. - Study the impact of beneficial/deleterious bacteria on spermatozoa physiology.

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IMPORTANT ALERT

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