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Publications | Masters and Phd thesis

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Publications

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In Press | 2023 | 2022 | ...

In Press

Effect of Conventional and Ultrahigh Dose Rate FLASH Irradiations on Preclinical Tumor Models: A Systematic Analysis.

Böhlen T.T., Germond J.F., Petersson K., Ozsahin E.M., Herrera F.G., Bailat C., Bochud F., Bourhis J., Moeckli R., Adrian G. International journal of radiation oncology, biology, physics. Peer-reviewed.

[URN][DOI][Pmid][serval:BIB_E35A0EBD9890]

2023

3D-conformal very-high energy electron therapy as candidate modality for FLASH-RT: A treatment planning study for glioblastoma and lung cancer.

Böhlen T.T., Germond J.F., Traneus E., Vallet V., Desorgher L., Ozsahin E.M., Bochud F., Bourhis J., Moeckli R., 2023/09. Medical physics, 50 (9) pp. 5745-5756. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_AE91AE049264]

preview resource BIB_65710DEED677.P001

Independent Reproduction of the FLASH Effect on the Gastrointestinal Tract: A Multi-Institutional Comparative Study.

Valdés Zayas A., Kumari N., Liu K., Neill D., Delahoussaye A., Gonçalves Jorge P., Geyer R., Lin S.H., Bailat C., Bochud F. et al., 2023/04/02. Cancers, 15 (7) p. 2121. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_65710DEED677]

preview resource BIB_CB3AC2C2AFDE.P001

Toxicity, quality of life, and PSA control after 50 Gy stereotactic body radiation therapy to the dominant intraprostatic nodule with the use of a rectal spacer: results of a phase I/II study.

Cloitre M., Valerio M., Mampuya A., Rakauskas A., Berthold D., Tawadros T., Meuwly J.Y., Heym L., Duclos F., Vallet V. et al., 2023/04/01. The British journal of radiology, 96 (1145) p. 20220803. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_CB3AC2C2AFDE]

In Reply to Horst et al.

Böhlen T.T., Germond J.F., Bochud F., Bailat C., Moeckli R., Bourhis J., Vozenin M.C., Ozsahin E.M., 2023/03/15. International journal of radiation oncology, biology, physics, 115 (4) pp. 1007-1009. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_1EAB447A4311]

Salvage LATTICE radiotherapy for a growing tumour despite conventional radio chemotherapy treatment of lung cancer.

Kinj R., Casutt A., Nguyen-Ngoc T., Mampuya A., Schiappacasse L., Bourhis J., Huck C., Patin D., Marguet M., Zeverino M. et al., 2023/03. Clinical and translational radiation oncology, 39 p. 100557. Peer-reviewed.

[DOI][Pmid][serval:BIB_FD65C693CBE6]

preview resource BIB_DB540CCA7ED5.P001

Postoperative SBRT in the treatment of early-stage oropharyngeal and oral cavity cancers with high-risk margins: A dosimetric comparison of volumetric modulated arc therapy with or without non-coplanar arcs and acute toxicity outcomes from the STEREOPOSTOP GORTEC 2017-03 phase 2 trial.

Biau J., Lopez L., Thivat E., Casile M., Millardet C., Saroul N., Pham-Dang N., Molnar I., Bourhis J., Lapeyre M., 2023/01. Clinical and translational radiation oncology, 38 pp. 169-174. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_DB540CCA7ED5]

Pembrolizumab versus cetuximab concurrent with radiotherapy in patients with locally advanced squamous cell carcinoma of head and neck unfit for cisplatin (GORTEC 2015-01 PembroRad): a multicenter, randomized, phase II trial.

Tao Y., Biau J., Sun X.S., Sire C., Martin L., Alfonsi M., Prevost J.B., Modesto A., Lafond C., Tourani J.M. et al., 2023/01. Annals of oncology, 34 (1) pp. 101-110. Peer-reviewed.

[DOI][Pmid][serval:BIB_5988D0B3696F]

Case report: First-in-human combined low-dose whole-heart irradiation and high-dose stereotactic arrhythmia radioablation for immunosuppressive refractory cardiac sarcoidosis and ventricular tachycardia.

van der Ree M.H., Herrera Siklody C., Le Bloa M., Pascale P., Porretta A.P., Teres C.C., Solana Munoz J., Luca A., Domenichini G., Ozasahin M. et al., 2023. Frontiers in cardiovascular medicine, 10 p. 1213165. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_FA14CF085E93]

2022

Normal Tissue Sparing by FLASH as a Function of Single-Fraction Dose: A Quantitative Analysis.

Böhlen T.T., Germond J.F., Bourhis J., Vozenin M.C., Ozsahin E.M., Bochud F., Bailat C., Moeckli R., 2022/12/01. International journal of radiation oncology, biology, physics, 114 (5) pp. 1032-1044. Peer-reviewed.

[DOI][Pmid][serval:BIB_03FA7A108554]

The minimal FLASH sparing effect needed to compensate the increase of radiobiological damage due to hypofractionation for late-reacting tissues.

Böhlen T.T., Germond J.F., Bourhis J., Bailat C., Bochud F., Moeckli R., 2022/12. Medical physics, 49 (12) pp. 7672-7682. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_A5B6F25E2105]

AIRO GORTEC consensus on postoperative radiotherapy (PORT) in low-intermediate risk early stages oral squamous cell cancers (OSCC).

Merlotti A., Alterio D., Orlandi E., Racadot S., Bonomo P., Franco P., D'Angelo E., Ursino S., Pointreau Y., Lapeyre M. et al., 2022/12. Radiotherapy and oncology, 177 pp. 95-104. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_A8EE44EDCADD]

Towards clinical translation of FLASH radiotherapy.

Vozenin M.C., Bourhis J., Durante M., 2022/12. Nature reviews. Clinical oncology, 19 (12) pp. 791-803. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_7711B81AAACB]

Refractory ventricular tachycardia treated by a second session of stereotactic arrhythmia radioablation.

Herrera Siklody C., Pruvot E., Pascale P., Kinj R., Jumeau R., Le Bloa M., Teres C., Domenichini G., Porretta A.P., Ozsahin M. et al., 2022/11. Clinical and translational radiation oncology, 37 pp. 89-93. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_0DB36A9EB031]

VoiceS: voice quality after transoral CO<sub>2</sub> laser surgery versus single vocal cord irradiation for unilateral stage 0 and I glottic larynx cancer-a randomized phase III trial.

Reinhardt P., Giger R., Seifert E., Shelan M., Riggenbach E., Terribilini D., Joosten A., Schanne D.H., Aebersold D.M., Manser P. et al., 2022/10/27. Trials, 23 (1) p. 906. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_AA7128E6DDF6]

Dose- and Volume-Limiting Late Toxicity of FLASH Radiotherapy in Cats with Squamous Cell Carcinoma of the Nasal Planum and in Mini Pigs.

Rohrer Bley C., Wolf F., Gonçalves Jorge P., Grilj V., Petridis I., Petit B., Böhlen T.T., Moeckli R., Limoli C., Bourhis J. et al., 2022/09/01. Clinical cancer research, 28 (17) pp. 3814-3823. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_83A4D24300BD]

preview resource BIB_3BC621CB1990.P001

Comparison of ultra-high versus conventional dose rate radiotherapy in a patient with cutaneous lymphoma.

Gaide O., Herrera F.G., Jeanneret Sozzi W., Gonçalves Jorge P., Kinj R., Bailat C., Duclos F., Bochud F., Germond J.F., Gondré M. et al., 2022/09. Radiotherapy and oncology, 174 pp. 87-91. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_3BC621CB1990]

preview resource BIB_86D6807F70CB.P001

Commissioning and validation of RayStation treatment planning system for CyberKnife M6.

Gondré M., Conrad M., Vallet V., Bourhis J., Bochud F., Moeckli R., 2022/08. Journal of applied clinical medical physics, 23 (8) pp. e13732. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_86D6807F70CB]

preview resource BIB_DBBB9D3370A5.P001

Low-dose irradiation for reversing immunotherapy resistance: how to translate?

Ochoa-de-Olza M., Bourhis J., Coukos G., Herrera F.G., 2022/07. Journal for immunotherapy of cancer, 10 (7) pp. e004939. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_DBBB9D3370A5]

International assessment of interobserver reproducibility of flap delineation in head and neck carcinoma.

Beddok A., Guzene L., Coutte A., Thomson D., Yom S.S., Calugaru V., Blais E., Gilliot O., Racadot S., Pointreau Y. et al., 2022/06. Acta oncologica, 61 (6) pp. 672-679. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_ECADD78C324F]

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Phd thesis

Publications (3)

Study and modulation of the immune microenvironment in a pre-clinical lung cancer model to optimize radiation-therapy efficiency.

Boivin Gael, Vozenin Marie-Catherine, 2019., Université de Lausanne, Faculté de biologie et médecine, Bourhis Jean (dir.).

[serval:BIB_AB942FA3E259]

preview resource BIB_1C9878253833.P002

Normal Brain, Neural Stem Cells and Glioblastoma Responses to FLASH Irradiation

Montay-Gruel Pierre, 2018/08/24. 258, Université de Lausanne, Faculté de biologie et médecine, Vozenin Marie-Catherine (dir.).

[URN][serval:BIB_1C9878253833]

Epigenetic conséquences and therapeutic implications of ERG transcriptional activation in prostate cancer

Zoma Marita, 2018., Université de Lausanne, Faculté de biologie et médecine, Bourhis Jean (dir.).

[serval:BIB_71C6E011D8B5]

Funding, Resources & Links

Funding	Fondation ISREC Fond’Action Fond National Suisse
Affiliations	Lausanne University Hospital - CHUV
Links	Biography of Jean Bourhis (UNIL/2013, in French) Interview of Jean Bourhis (UNIL/Faculty of Biology & Medicine/2020, in French) 3 Questions to Jean Bourhis (Lausanne University Hospital/2020, in French) Contributions to Revue Médicale Suisse Media compilation @Planète Santé

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Jean BOURHIS
Full Professor
Laboratory J. Bourhis

Department of oncology UNIL CHUV

Phone +41 21 314 46 66
Fax +41 21 314 46 01
Email

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