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Publications | Masters and Phd thesis

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In Press | 2024 | 2023 | ...

In Press

Survival without Quality of Life Deterioration in the GORTEC 2014-04 "OMET" Randomised Phase 2 Trial in Head and Neck Cancer Patients with Oligometastases using Stereotactic Ablative Radiotherapy (SABR)-alone or chemotherapy SABR.

Thariat J., Bosset M., Falcoz A., Vernerey D., Pointreau Y., Racadot S., Faivre J.C., Castelli J., Guihard S., Huguet F. et al. International journal of radiation oncology, biology, physics. Peer-reviewed.

[DOI][Pmid][serval:BIB_F3A45574859E]

2024

preview resource BIB_26C0B35C8AAC.P001

Hybrid ultra-high and conventional dose rate treatments with electrons and photons for the clinical transfer of FLASH-RT to deep-seated targets: A treatment planning study.

Böhlen T.T., Zeverino M., Germond J.F., Kinj R., Schiappacasse L., Bochud F., Herrera F., Bourhis J., Moeckli R., 2024/12. Radiotherapy and oncology, 201 p. 110576. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_26C0B35C8AAC]

preview resource BIB_CEC8943C833B.P001

Validation of MLC leaf open time calculation methods for PSQA in adaptive radiotherapy with tomotherapy units.

Nasrallah M., Bochud F., Tellapragada N., Bourhis J., Chao E., Casey D., Moeckli R., 2024/10. Journal of applied clinical medical physics, 25 (10) pp. e14478. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_CEC8943C833B]

preview resource BIB_F5AFF8A3C19B.P001

Standard versus fractionated high-dose cisplatin plus radiation for locally advanced head and neck cancer: Results of the CisFRad (GORTEC 2015-02) randomized phase II trial.

Borel C., Sun X.S., Coutte A., Bera G., Sire C., Zanetta S., Alfonsi M., Janoray G., Chatellier T., Garcia-Ramirez M. et al., 2024/08. Radiotherapy and oncology, 197 p. 110329. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_F5AFF8A3C19B]

preview resource BIB_928A3D4544F6.P001

Sensitivity of automated and manual treatment planning approaches to contouring variation in early-breast cancer treatment.

Zeverino M., Piccolo C., Marguet M., Jeanneret-Sozzi W., Bourhis J., Bochud F., Moeckli R., 2024/07. Physica medica, 123 p. 103402. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_928A3D4544F6]

preview resource BIB_FC7E3ACA49E0.P001

Adapted EXTREME regimen in the first-line treatment of fit, older patients with recurrent or metastatic head and neck squamous cell carcinoma (ELAN-FIT): a multicentre, single-arm, phase 2 trial.

Guigay J., Le Caer H., Ferrand F.R., Geoffrois L., Saada-Bouzid E., Fayette J., Sire C., Cupissol D., Blot E., Guillet P. et al., 2024/06. The lancet. Healthy longevity, 5 (6) pp. e392-e405. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_FC7E3ACA49E0]

preview resource BIB_F69D11E34A2A.P001

Spatial Distribution of Recurrence and Long-Term Toxicity Following Dose Escalation to the Dominant Intra-Prostatic Nodule for Intermediate-High-Risk Prostate Cancer: Insights from a Phase I/II Study.

Cloître M., Benkhaled S., Boughdad S., Schaefer N., Prior J.O., Zeverino M., Berthold D., Tawadros T., Meuwly J.Y., Martel P. et al., 2024/05/31. Cancers, 16 (11). Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_F69D11E34A2A]

preview resource BIB_825ACAC4F6E5.P001

Very high-energy electron therapy as light-particle alternative to transmission proton FLASH therapy - An evaluation of dosimetric performances.

Böhlen T.T., Germond J.F., Desorgher L., Veres I., Bratel A., Landström E., Engwall E., Herrera F.G., Ozsahin E.M., Bourhis J. et al., 2024/05. Radiotherapy and oncology, 194 p. 110177. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_825ACAC4F6E5]

preview resource BIB_51F2E37A9F70.P001

Long-Term Results of Stereotactic Radiotherapy in Patients with at Least 10 Brain Metastases at Diagnosis.

Kinj R., Hottinger A.F., Böhlen T.T., Ozsahin M., Vallet V., Dunet V., Bouchaab H., Peters S., Tuleasca C., Bourhis J. et al., 2024/04/29. Cancers, 16 (9). Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_51F2E37A9F70]

Proposition de délinéation des volumes cibles anatomocliniques postopératoires de la tumeur primitive des cancers du sinus maxillaire et des cavités nasales [Proposal for the delineation of postoperative primary clinical target volumes in maxillary sinus and nasal cavity cancers]

Guillemin F., Blanchard P., Boisselier P., Brahimi Y., Calugaru V., Coutte A., Gillon P., Graff P., Liem X., Modesto A. et al., 2024/04. Cancer radiotherapie, 28 (2) pp. 218-227. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_1A80814091A3]

preview resource BIB_49E1CA979679.P001

Comparison of volumetric modulated arc therapy and helical tomotherapy for prostate cancer using Pareto fronts.

Wüthrich D., Wang Z., Zeverino M., Bourhis J., Bochud F., Moeckli R., 2024/04. Medical physics, 51 (4) pp. 3010-3019. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_49E1CA979679]

preview resource BIB_167AAFE038E3.P001

Cetuximab versus methotrexate in first-line treatment of older, frail patients with inoperable recurrent or metastatic head and neck cancer (ELAN UNFIT): a randomised, open-label, phase 3 trial.

Guigay J., Ortholan C., Vansteene D., Cupissol D., Even C., Kaminsky M.C., Sire C., Blot E., Debourdeau P., Bozec L. et al., 2024/03. The lancet. Healthy longevity, 5 (3) pp. e182-e193. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_167AAFE038E3]

preview resource BIB_A13C0D7F4DC1.P001

Randomized phase II selection trial of FLASH and conventional radiotherapy for patients with localized cutaneous squamous cell carcinoma or basal cell carcinoma: A study protocol.

Kinj R., Gaide O., Jeanneret-Sozzi W., Dafni U., Viguet-Carrin S., Sagittario E., Kypriotou M., Chenal J., Duclos F., Hebeisen M. et al., 2024/03. Clinical and translational radiation oncology, 45 p. 100743. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_A13C0D7F4DC1]

Season of radiotherapy and outcomes of head & neck cancer patients in the MACH-NC & MARCH meta-analyses.

Limkin E., Blanchard P., Lacas B., Bourhis J., Parmar M., Licitra L., Le Q.T., Yom S.S., Fortpied C., Langendijk J. et al., 2024/01. Radiotherapy and oncology, 190 p. 110011. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_3FB310A6F592]

Letter to the Editor: SMAC mimetics inhibit human T cell proliferation and fail to augment type 1 cytokine responses.

Bourhis J., Sun X.S., Tao Y., 2024. Cellular immunology, 395-396 p. 104772. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_988F5287887C]

2023

Effect of Conventional and Ultrahigh Dose Rate FLASH Irradiations on Preclinical Tumor Models: A Systematic Analysis.

Böhlen T.T., Germond J.F., Petersson K., Ozsahin E.M., Herrera F.G., Bailat C., Bochud F., Bourhis J., Moeckli R., Adrian G., 2023/11/15. International journal of radiation oncology, biology, physics, 117 (4) pp. 1007-1017. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_E35A0EBD9890]

Need for standardization in the use of structures in the intensity-modulated radiation therapy planning of head and neck cancers, a GORTEC study.

Özer Ö., Shafi H., O'Reilly D., Loiseau C., Dejean C., Bourhis J., Thariat J., 2023/11. Radiotherapy and oncology, 188 p. 109895. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_1B42004D5655]

preview resource BIB_7FC036C4B1A6.P001

Influence of optimisation parameters on directly deliverable Pareto fronts explored for prostate cancer.

Wüthrich D., Zeverino M., Bourhis J., Bochud F., Moeckli R., 2023/10. Physica medica, 114 p. 103139. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_7FC036C4B1A6]

preview resource BIB_03629A515559.P001

Clinical implementation of deep learning-based automated left breast simultaneous integrated boost radiotherapy treatment planning.

Zeverino M., Piccolo C., Wuethrich D., Jeanneret-Sozzi W., Marguet M., Bourhis J., Bochud F., Moeckli R., 2023/10. Physics and imaging in radiation oncology, 28 p. 100492. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_03629A515559]

preview resource BIB_AE91AE049264.P001

3D-conformal very-high energy electron therapy as candidate modality for FLASH-RT: A treatment planning study for glioblastoma and lung cancer.

Böhlen T.T., Germond J.F., Traneus E., Vallet V., Desorgher L., Ozsahin E.M., Bochud F., Bourhis J., Moeckli R., 2023/09. Medical physics, 50 (9) pp. 5745-5756. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_AE91AE049264]

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Phd thesis

Publications (3)

Study and modulation of the immune microenvironment in a pre-clinical lung cancer model to optimize radiation-therapy efficiency.

Boivin Gael, Vozenin Marie-Catherine, 2019., Université de Lausanne, Faculté de biologie et médecine, Bourhis Jean (dir.).

[serval:BIB_AB942FA3E259]

preview resource BIB_1C9878253833.P002

Normal Brain, Neural Stem Cells and Glioblastoma Responses to FLASH Irradiation

Montay-Gruel Pierre, 2018/08/24. 258, Université de Lausanne, Faculté de biologie et médecine, Vozenin Marie-Catherine (dir.).

[URN][serval:BIB_1C9878253833]

Epigenetic conséquences and therapeutic implications of ERG transcriptional activation in prostate cancer

Zoma Marita, 2018., Université de Lausanne, Faculté de biologie et médecine, Bourhis Jean (dir.).

[serval:BIB_71C6E011D8B5]

Funding, Resources & Links

Funding	Fondation ISREC Fond’Action Fond National Suisse
Affiliations	Lausanne University Hospital - CHUV
Links	Biography of Jean Bourhis (UNIL/2013, in French) Interview of Jean Bourhis (UNIL/Faculty of Biology & Medicine/2020, in French) 3 Questions to Jean Bourhis (Lausanne University Hospital/2020, in French) Contributions to Revue Médicale Suisse Media compilation @Planète Santé

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Jean BOURHIS
Full Professor
Laboratory J. Bourhis

Department of oncology UNIL CHUV

Phone +41 21 314 46 03
Fax +41 21 314 46 01
Email

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