Postdoctoral researcher |
Research interest
My focus is on how metabolic regulation controls cancer metastasis and T cell exhaustion.
Background
I studied epigenomic regulation and bioinformatic analysis in cancer during my master’s at the Institute of Biomedical Sciences, National Chung Cheng University, Taiwan.
My current research focuses on preventing T cell acquired dysfunction (named T cell exhaustion), which is linked to reduced antitumor responses. Since we know that these dysfunctional T cells accumulate damaged mitochondria, we are studying potential new targets to enhance T cell mitochondrial fitness in the tumor microenvironment.
I obtained my bachelor's degree in Biology-Genetics from the Federal University of Rio de Janeiro (Brazil) and my master's degree in Immunology from the Brazilian National Cancer Institute. During my previous research, I helped develop an ultra-fast protocol for the generation of chimeric antigen receptor (CAR)-T cells using transposon-based systems. I joined the Ho Lab for my PhD studies in May 2023.
Research interest
My expertise is in working with the proteomics and metabolomics analysis. Aging leads to a progressive functional decline in T cell anti-tumor responses, new information about this process will be valuable to the restoring and/or sustaining of T cell functions. My interest is to elucidate the mechanism in T cell aging and our goal unleash anti-tumor immunity by modulating the T cell metabolism.
Background
I studied at Chang Gung University, Taiwan for my BSc through to my PhD.
PhD student |
Research interest
Metabolic adapatation of regulatory T cells in tumors.
Background
University of Lausanne, Department of Oncology: PhD student / 2020-Present
University of Zurich, Institute of Experimental Immunology: PhD student /2019 - 2020
National Taiwan University, Graduate Institute of Immunology: Research assistant / 2014 - 2019
National Taiwan University, Graduate Institute of Immunology: MSc/ 2012 - 2014
National Chung Hsing University, Bachelor Program of Biotechnology: BSc. / 2008 - 2012
PhD student |
Research interest
Background
Research interest
I am currently interested in understanding the impact of the gut microbiota on the anti-cancer immune response, focusing on the role of myeloid cells in particular.
Background
I have a Master’s degree in Molecular Biomedicine and during my PhD I investigated the metabolic regulation of immune stimulatory NKG2D ligands in the lab of Søren Skov at the University of Copenhagen.
PhD student |
Research interest
My current interest is in metabolic adaptation during CD8 T cell memory differentiation.
Background
I am studying medicine at the University of Lausanne and undertaking an MD-PhD.
Laboratory manager |
Research interest
As lab manager and coordinator, I am dedicated to creating an organised working environment for our researchers and providing help on fundamental lab issues.
Background
I finished two Master's degrees, one was at National Taiwan University, which built up my basic biochemistry knowledge and techniques. The other, at University of Minnesota, provided me with important pharmacology knowledge and a chance to explore broader fields in research including neuroscience and stem cell. I then worked on an Immunobiology program at Yale University as a research technician where I filled an assistant role in research and enjoyed the achievement of resolving technical problems to help along the entire team.
Postdoctoral researcher |
Research interest
My interest focuses on the crosstalk between intratumoral dendritic cells and CD8+ T cells and epigenetic editing of T cells with CRISPR tools.
Background
I obtained my Bachelor's degree in Biology at the University of Geneva. I then did my Master's in Medical Biology with a specialization in Cancer and Immunology at the University of Lausanne.
Postdoctoral researcher |
Postdoctoral researcher |
Research interest
My major topic is the metabolic programming in dendritic cells and T cells mediates immune responses and homeostasis.
Background
I received my PhD in 2018 from the University of Bern’s Department of BioMedical research, focusing on identifying mesenchymal and epithelial progenitor cell subtypes, tumor microenvironment and uncovering the molecular underpinnings of T cell exhaustion in human cancer. I worked at Harvard Medical School as a postdoctoral fellow for one year before joining the Ho Lab in September 2020.
Postdoctoral researcher |
Research interest
I am interested in exploring the messenger between dysfunctional mitochondria and epigenetic reprogramming in exhausted T cells.
Background
I did my PhD at the medical school of Nankai University (China). I then worked on a hematologic oncology program at the Institute of Hematology and Blood Diseases Hospital in China where I focused on investigating CAR T cell immunotherapy for leukemia.
Ping-Chih HO
Full Professor
Ludwig member
Laboratory P-C. Ho
Department of oncology UNIL CHUV
Ludwig Institute for Cancer Research Lausanne
Phone +41 21 692 59 47
E-mail
Centre de Laboratoire Epalinges (CLE)
Ch. des Boveresses 155
CH-1066 Epalinges
Switzerland