Ho Lab members

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Francesca ALFEI
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Postdoctoral researcher
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Research interest 

Understanding the crosstalk between dendritic cells and T-cells in tailoring CD8+ T cell anti-tumor responses.

Background 

I studied Medical Biotechnology at the University of Rome “Sapienza” and obtained my PhD in Life Science at the Technical University of Munich.

Alessio BEVILACQUA
Ho Lab Alessio Bevilacqua-crop201x194.jpeg PhD student
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Research interest

Metabolic reprogramming in memory and exhausted T cells.

Background

Master’s in Biomedical Sciences from the Université Catholique de Louvain.

Yu-Ming CHUANG
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PhD student
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Research interest 

My focus is on how metabolic regulation controls cancer metastasis and T cell exhaustion.

Background 

I studied epigenomic regulation and bioinformatic analysis in cancer during my master’s at the Institute of Biomedical Sciences, National Chung Cheng University, Taiwan.

Giusy DI CONZA
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Postdoctoral researcher
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Research interest 

Cancer biology has been the focus of my research during my doctoral and postdoctoral training. In the Ho Lab, by exploring a metabolic angle of intratumoral interactions, I am studying how cancer cells sustain their growth by shaping macrophage towards an immunosuppressive phenotype through release of specific lipids.

Background 

  • Master's degree in ‘Medical Biotechnology’, University ‘Sapienza’ of Rome.

  • PhD in Experimental Endocrinology and Metabolic Disease, University of Messina/CNR- Ist. of Cell Biology, Rome.

  • Postdoc (FWO-Marie Curie Fellow) at the VIB, KU Leuven.

Fabien FRANCO
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PhD student
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Research interest 

I am interested in understanding the role of metabolism during CD8 T cell differentiation. I specifically focus on determining the role of mitochondria recycling during formation of memory T cells. 

Background 

I studied biology at the University of Lausanne. After the Bachelor’s degree, I did my Master's in Medical Biology, still in Lausanne.

Pei-Chun HSUEH
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Postdoctoral researcher
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Research interest 

My expertise is in working with the proteomics and metabolomics analysis. Aging leads to a progressive functional decline in T cell anti-tumor responses, new information about this process will be valuable to the restoring and/or sustaining of T cell functions. My interest is to elucidate the mechanism in T cell aging and our goal unleash anti-tumor immunity by modulating the T cell metabolism.

Background 

I studied at Chang Gung University, Taiwan for my BSc through to my PhD.

Kung-Chi KAO
Ho Lab Kung-Chi Kao-crop384x400.jpg PhD student
CONTACT ME

Research interest 

Metabolic adapatation of regulatory T cells in tumors.

Background

  • University of Lausanne, Department of Oncology: PhD student / 2020-Present

  • University of Zurich, Institute of Experimental Immunology: PhD student /2019 - 2020

  • National Taiwan University, Graduate Institute of Immunology: Research assistant / 2014 - 2019

  • National Taiwan University, Graduate Institute of Immunology: MSc/ 2012 - 2014

  • National Chung Hsing University, Bachelor Program of Biotechnology: BSc. / 2008 - 2012

Xiaoyun LI
Ho Lab Xiaoyun Li-crop367x371.jpeg PhD student
CONTACT ME

Research interest 

I am working on delineating how the metabolic crosstalk between cancer-associated fibroblasts and cancer cell instructing the polarization of macrophages in tumors.

Background 

I obtained my Bachelor’s degree and Master’s in Soochow University, China, joining the University of Lausanne for my PhD.

Zhiyu LI
Ho Lab Zhiyu Li-crop675x634.JPG Visiting scientist
CONTACT ME

Research interest 

Metabolic checkpoint in dendritic cell behaviour. 

Background 

Clinical study in breast cancer; tumor metabolism and microenvironment. I graduated from Wuhan University, majoring breast and thyroid surgery.

Wenfeng LIU
HO Lab Wenfeng Liu-crop597x618.jpg PhD student
CONTACT ME

Research interest 

I'm very intrigued by the metabolic adaptation of T cells in tumor microenvironment and the crosstalk among T cells and other types of immune cells.

Background 

I majored in pharmacology and specialized in oncolytic virus and tumor immunology during my master's at Sun Yat-sen University (PRC).

Jaeoh PARK
Oncology Lausanne Ho Lab Jaeoh Park.jpg Postdoctoral researcher
CONTACT ME

Research interest 

I am interested in understanding the biology of myeloid cells in hepatocellular carcinoma.

Background 

I studied the regulation of Hippo pathway in pancreatic cancer during my PhD at the Korea Advanced Institute of Science and Technology (KAIST).

Sophie Hedlund MOLLER
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Postdoctoral researcher
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Research interest 

I am currently interested in understanding the impact of the gut microbiota on the anti-cancer immune response, focusing on the role of myeloid cells in particular.

Background 

I have a Master’s degree in Molecular Biomedicine and during my PhD I investigated the metabolic regulation of immune stimulatory NKG2D ligands in the lab of Søren Skov at the University of Copenhagen.

Pia NEUBERT
Ho Lab Pia Neubert-crop474x469.jpg Intern
CONTACT ME

Research interest 

T cell exhaustion and mitochondrial biology in T cells in chronic viral infection. 

Background

I have an MSc in Medical Biology from the University Lausanne with a major in Immunology and Cancer.

Lorène ROUSSEAU
Oncology Lausanne Ho Lab Lorène Rousseau-crop1144x1122.jpg PhD student
CONTACT ME

Research interest 

My current interest is in metabolic adaptation during CD8 T cell memory differentiation. 

Background 

I am studying medicine at the University of Lausanne and undertaking an MD-PhD. 

Johannes SCHWENK
Oncology Lausanne Ho Lab Johannes Schwenck-crop1883x1897.jpg Postdoctoral researcher
CONTACT ME

Research interest 

My main interests are inflammatory processes such as non-alcoholic steatohepatitis (NASH) and inflammation driven carcinogenesis.

Background 

I studied medicine at the University of Tübingen (Germany) where I focused on preclinical and translational imaging research in inflammation and cancer, as well as on clinical health care in the course of my MD/PhD at the University Hospital of Tübingen.

Yao-Chen TSUI
Oncology Lausanne Ho Lab Yao Chen Tsui-crop1167x1194.JPG Laboratory manager
CONTACT ME

Research interest 

As lab manager and coordinator, I am dedicated to creating an organised working environment for our researchers and providing help on fundamental lab issues.

Background 

I finished two Master's degrees, one was at National Taiwan University, which built up my basic biochemistry knowledge and techniques. The other, at University of Minnesota, provided me with important pharmacology knowledge and a chance to explore broader fields in research including neuroscience and stem cell. I then worked on an Immunobiology program at Yale University as a research technician where I filled an assistant role in research and enjoyed the achievement of resolving technical problems to help along the entire team. 

Stefania VILBOIS
Oncology Lausanne Ho Lab Stefania Vilbois-crop485x541.jpg Postdoctoral researcher
CONTACT ME

Research interest 

My interest focuses on the crosstalk between intratumoral dendritic cells and CD8+ T cells and epigenetic editing of T cells with CRISPR tools.

Background 

I obtained my Bachelor's degree in Biology at the University of Geneva. I then did my Master's in Medical Biology with a specialization in Cancer and Immunology at the University of Lausanne.

Limei WANG
Ho Lab Limei Wang-crop471x447.JPG Postdoctoral researcher
CONTACT ME

Research interest 

My major topic is the metabolic programming in dendritic cells and T cells mediates immune responses and homeostasis.

Background 

I received my PhD in 2018 from the University of Bern’s Department of BioMedical research, focusing on identifying mesenchymal and epithelial progenitor cell subtypes, tumor microenvironment and uncovering the molecular underpinnings of T cell exhaustion in human cancer. I worked at Harvard Medical School as a postdoctoral fellow for one year before joining the Ho Lab in September 2020.

Yingxi XU
Oncology Lausanne Ho Lab Yingxi Xu-2020-crop697x656.jpg Postdoctoral researcher
CONTACT ME

Research interest 

I am interested in exploring the messenger between dysfunctional mitochondria and epigenetic reprogramming in exhausted T cells. 
 

Background 

I did my PhD at the medical school of Nankai University (China). I then worked on a hematologic oncology program at the Institute of Hematology and Blood Diseases Hospital in China where I focused on investigating CAR T cell immunotherapy for leukemia. 

Yi-Ru YU
Ho Lab Yi-Ru Yu-crop333x355.jpg Postdoctoral researcher
CONTACT ME

Research interest 

My current interest is to dissect the unidentified metabolic crosstalk between T cells and malignant cells in the tumor microenvironment and provide pillows for the potential therapeutic applications.

Background 

During my PhD studies, I focused on the role of ovarian cancer gene 1 (Ovca1) in congenital disease and tumorigenesis as a mouse geneticist in National Yang-Ming University in Taiwan. Currently, I’m working on the role of dysfunctional mitochondria in T cell exhaustion in the tumor microenvironment in UNIL.

Alison JACCARD
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PhD student
CONTACT ME

Research interest

T cell metabolic and epigenetic reprogramming to improve adoptive cell transfer immunotherapy.

Background

I did my Master’s in Medical Biology in the immunology and cancer program at the University of Lausanne. I had the opportunity to do my master’s work in the laboratory of Pr Pedro Romero and was very happy to continue with a PhD, under the co-supervision of Pr Ping-Chih Ho.

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CONTACT

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Ping-Chih HO
Associate Professor
Ludwig associate member
Laboratory P-C. Ho

Department of oncology UNIL CHUV
Ludwig Institute for Cancer Research Lausanne

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Phone +41 21 692 59 47
E-mail

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The Ho Lab is based at:

Centre de Laboratoire Epalinges (CLE)
Ch. des Boveresses 155
CH-1066 Epalinges
Switzerland

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Ch. des Boveresses 155 - CH-1066 Epalinges
Switzerland
Tel. +41 21 692 59 92
Fax +41 21 692 59 95
Ludwig Cancer Research Université de Lausanne Centre Hospitalier Universitaire Vaudois (CHUV)